Fixed-Wavelength UV Photometry: Measurement Constraints at High Protein Concentrations in Bioprocessing
As biomanufacturing moves toward higher-titer processes and concentrated mAb formulations, the measurement tools standard in most facilities are reaching their limits. Fixed-wavelength UV photometers — workhorses of chromatography and downstream processing for decades — are not designed for the concentration ranges modern bioprocessing now demands. Knowing where and why those limitations occur is the first … Continued
Read more